More hope for would-be parents? Many embryos ruled out in IVF “self-correct”
Reproductive Health Assisted Reproductive Technology IVF

More hope for would-be parents? Many embryos ruled out in IVF “self-correct”

Dr. Ralph Papas
Dr. Ralph Papas

In 10 seconds? Some ‘faulty’ embryos that are normally discarded in IVF can self-correct in the womb and result in healthy pregnancies. So-called ‘aneuploid embryos’ are flagged up in a genetic test before implantation. The finding could improve women’s chances of having healthy pregnancies.

So, what does the research say? According to a clinical study from April 2021, aneuploid embryos can actually result in healthy babies, suggesting the presence of an in vivo (in the womb) mechanism to eliminate aneuploidy – the abnormal chromosomal count that up to now has been a red flag stopping the implantation of such embryos in the womb. The study described 32 women who agreed to receive blastocysts (fertilized eggs that are rapidly on their way to becoming an embryo) that came up as aneuploid in PGT-A testing. A few months after the transfer, prenatal pregnancy testing revealed that all traces of aneuploidy had vanished and that embryos were now normal! The live birth rates of these mothers ultimately matched the national averages for women who received “euploid” embryos that passed the PGT-A test.

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