'Nanobombs' improve drug delivery, including for Covid vaccines
Lipid Nanoparticle COVID Vaccine Cancer

'Nanobombs' improve drug delivery, including for Covid vaccines

Dr Rohan Shah
Dr Rohan Shah

In 10 seconds? Microwave heat can create nanoparticles to precisely deliver drugs inside the body, vital for Covid-vaccines and improving cancer chemotherapy.

So, what’s the breakthrough? Researchers used microwave heat to produce solid lipid nanoparticles (SLNs) faster and with dramatically improved properties when compared with the conventional, thermal heat method. Microwave heat can create particles that are more stable, smaller and encapsulate the drug load much better.

Let's slow down, what's the use of these 'nanoparticles'? They are a step forward in medicine and have made mRNA Covid vaccines possible. Tens of thousands of times smaller than the width of a human hair, nanoparticles can deliver and control the release of drugs in the human body in a much more precise way than conventional carriers. The way modern drugs reach their target and are kept chemically stable en route is as important as how they work. This is where nanoparticles come into play.

Lipid nanoparticles are versatile drug delivery vehicles that safely dissolve in the body. Source: Pimentel-Moral, Teixeira, Fernandes et al, 2018.
Lipid nanoparticles are versatile drug delivery vehicles that safely dissolve in the body. Source: Pimentel-Moral, Teixeira, Fernandes et al, 2018.

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