Nanobodies: A new therapeutic approach against Covid-19
COVID-19 Nanobody ACE2 Receptor

Nanobodies: A new therapeutic approach against Covid-19

Santhni Subramaniam
Santhni Subramaniam

In 10 seconds? The Covid-19 pandemic has seen various vaccines rolled out across the globe. However, their effectiveness varies against new viral strains. Emerging ‘nanobody’ therapies can offer a prophylactic option but they will take years to authorise.

I know about antibodies but what are these nanobodies? OK, so antibodies are complex protein molecules that specifically act on 'antigens'. In the case of Covid-19 the antigens are parts of the SARS-CoV-2 virus that can provoke an immune reaction. However, when it comes to binding to and disabling the virus, nanobodies can be more effective. One reason is due to their size – they are not called ‘nano’ for nothing! Nanobodies are the smallest fragments of antibodies and specifically bind to the notorious spike protein that SARS-CoV-2 uses to enter our cells. Through this binding, they neutralise the virus and block infection.

Get unlimited access to our 3-min Digests and other premium features

Choose your plan:

Personal

$99/year

✅ Includes 7-day free trial for new users
✅ Weekly Recap
✅ Daily newsletter
✅ Access 4 topic areas of your choosing
✅ Access all citations and resources
✅ Gain background knowledge with a Quick Dive
✅ The Sparrow Sessions Podcast
✅ No ads
❌ Direct access to the Expert Network
❌ Your questions - answered by an Expert Scientist
❌ 12 hours of consultations with our fabulous experts per year (that’s 1 hour per month!)
❌ Access to all topic areas as we scale the Content Library

We'll send you a reminder email 3 days before your trial ends.

Start my free trial

Professional

$3499/year

✅ Includes 7-day free trial for new users
✅ Weekly Recap
✅ Daily newsletter
✅ Access all citations and resources
✅ Gain background knowledge with a Quick Dive
✅ The Sparrow Sessions Podcast
✅ No ads
✅ Direct access to the Expert Network
✅ Your questions - answered by an Expert Scientist
✅ 12 hours of consultations with our fabulous experts per year (that’s 1 hour per month!)
✅ Access to all topic areas as we scale the Content Library

We'll send you a reminder email 3 days before your trial ends.

Start my free trial